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FDA approves once-weekly insulin injection for type 2 diabetes

The FDA approved Eli Lilly's efsitora (Onswik), a once-weekly basal insulin for adults with type 2 diabetes, giving patients an alternative to daily long-acting insulin injections.

By The Lumen desk · Sept 26, 2026 · 1 min read
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What we know
1 The FDA approved efsitora (Onswik), a once-weekly basal insulin made by Eli Lilly.
2 It is indicated for adults with type 2 diabetes as an adjunct to diet and exercise.
3 It offers an alternative to daily long-acting insulin injections, according to STAT.
4 According to the New York Post, Eli Lilly said the drug could cut injections by more than 300 per year compared with once-daily basal insulin.

The FDA has approved efsitora, sold under the brand name Onswik, a once-weekly basal insulin for adults with type 2 diabetes, according to Eli Lilly's announcement reported by multiple outlets.

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The drug is indicated as an adjunct to diet and exercise and is designed to deliver steady basal insulin over a week, according to MedPage Today.

STAT reported the approval gives patients an alternative to daily long-acting insulin injections.

According to the New York Post, the once-weekly treatment could reduce the number of injections by more than 300 per year compared with once-daily basal insulin, per Eli Lilly.

How each side covered it

Center

2 outlets
  • MedPage Today reported the FDA approved Eli Lilly's once-weekly basal insulin efsitora, branded Onswik, for adults with type 2 diabetes.
  • MedPage Today noted the drug is indicated as an adjunct to diet and exercise and delivers steady basal insulin.
  • STAT described the approval as giving patients an alternative to daily long-acting insulin injections.

“The FDA approved Eli Lilly’s Onswik, a once-weekly basal insulin for adults with type 2 diabetes, offering patients an alternative to daily long-acting insulin injections.” — STAT

Right

1 outlet
  • The New York Post emphasized the once-weekly treatment could cut injections by more than 300 per year compared with daily basal insulin, citing Eli Lilly.

“The once-weekly ​treatment could reduce the number of injections by more ⁠than 300 per year compared with once-daily basal insulin, ​Eli Lilly said.” — New York Post

Questions readers ask

What did the FDA approve?

The FDA approved efsitora, sold as Onswik, a once-weekly basal insulin made by Eli Lilly for adults with type 2 diabetes, according to MedPage Today and STAT.

How is this different from existing insulin treatments?

Efsitora is administered once a week rather than daily, offering patients an alternative to daily long-acting insulin injections, according to STAT.

How much could this reduce injections?

According to the New York Post, citing Eli Lilly, the once-weekly treatment could reduce the number of injections by more than 300 per year compared with once-daily basal insulin.

Who is the drugmaker behind Onswik?

Eli Lilly developed efsitora (Onswik) and announced the FDA approval, according to MedPage Today and STAT.

Sources · 3 outlet reports

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